Journal Guide

musculoskeletal disorders, rheumatism and connective tissue diseases, rheumatism, connective tissue diseases

Review Process

Research in Middle Level Education Online (RMLE Online) uses a triple-blind review process. Manuscripts are initially reviewed by the Editor. Manuscripts that meet the journal's standards are forwarded to three reviewers who serve on the Editorial Review Board. A decision regarding publication is typically reached within two months of the date the manuscript is sent out for review. This decision is communicated to the corresponding author by email. 

RNA serves as an international forum for publishing original reports on RNA research in the broadest sense. The journal aims to unify this field by cutting across established disciplinary lines and focusing on "RNA-centered" science.RNA is a monthly journal which provides rapid publication of significant original research in all areas of RNA structure and function in eukaryotic, prokaryotic, and viral systems. It covers a broad range of subjects in RNA research, including: structural analysis by biochemical or biophysical means; mRNA structure, function and biogenesis; alternative processing: cis-acting elements and trans-acting factors; ribosome structure and function; translational control; RNA catalysis; tRNA structure, function biogenesis and identity; RNA editing; rRNA structure, function and biogenesis; RNA transport and localization; regulatory RNAs; large and small RNP structure, function and biogenesis; viral RNA metabolism; RNA stability and turnover; in vitro evolution; and RNA chemistry.RNA considers papers in six categories: Reports, Articles, Bioinformatics, Hypotheses, Methods, and Letters to the Editor. Reports document significant new results that lend themselves to succinct presentation (i.e., combined Results and Discussion) and can contain no more than four display items. Reports are evaluated using the same criteria as Articles; preliminary observations that require further experimentation to support the major conclusions will not be accepted. There are no explicit length limitations to Articles and length is not a criterion for evaluation. Bioinformatics describe computer-based analyses of sequence data or new informatic tools of interest to RNA scientists. Hypotheses outline novel concepts or new ways of integrating existing data. Methods are brief accounts of methodological advances or improvements that are of potential utility to a broad range of RNA researchers. Letters to the Editor are intended as a forum for raising or clarifying issues of specific interest to the RNA community.In addition to the categories above, RNA publishes Reviews, Perspectives, Mini-reviews, and Meeting Summaries. Normally, these are by invitation, but presubmission inquiries to the Reviews Editor are welcome.This journal is published by CSHL Press for RNA Society. Authors are not required to be members of the Society. Queries regarding editorial policies or manuscripts in review should be directed to the Editorial Office at rnajournal@case.edu.Subscription to the print journal includes full access to the online edition at http://www.rnajournal.org. (Online-only subscriptions are available to institutions.) A subscription to RNA is included with RNA Society membership. For more information about RNA Society and membership, visit RNA Society.

C. elegans RDE-4 is a double-stranded RNA binding protein that has been shown to play a key role in response to foreign double-stranded RNA (dsRNA). We have used diverse tools for analysis of gene function to characterize the domain and organismal foci of RDE-4 action in C. elegans. First, we examined the focus of activity within the RDE-4 protein, by testing a series of RDE-4 deletion constructs for their ability to support dsRNA-triggered gene silencing. These assays indicated a molecular requirement for a linker region and the second dsRNA-binding domain of RDE-4, with ancillary contributions to function from the C and N terminal domains. Second, we used mosaic.

Robotics and Automation, Mechatronics, Artificial Intelligence (incl. Robotics), Control, Computational Intelligence